Document Detail


Effects of stacking on the configurations and elasticity of single-stranded nucleic acids.
MedLine Citation:
PMID:  15447472     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Stacking interactions in single-stranded nucleic acids give rise to configurations of an annealed rod-coil multiblock copolymer. Theoretical analysis identifies the following resulting signatures for long homopolynucleotides: a nonmonotonic dependence of size on temperature, the corresponding effects on cyclization and a plateau in the extension force law. Explicit numerical results for polydeoxyadenylate [poly(dA)] and polyriboadenylate [poly(rU)] are presented.
Authors:
A Buhot; A Halperin
Publication Detail:
Type:  Journal Article     Date:  2004-08-24
Journal Detail:
Title:  Physical review. E, Statistical, nonlinear, and soft matter physics     Volume:  70     ISSN:  1539-3755     ISO Abbreviation:  Phys Rev E Stat Nonlin Soft Matter Phys     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2004-09-27     Completed Date:  2005-02-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101136452     Medline TA:  Phys Rev E Stat Nonlin Soft Matter Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  020902     Citation Subset:  IM    
Affiliation:
UMR 5819 (UJF, CNRS, CEA) DRFMC, CEA Grenoble, 17 rue des Martyrs, 38054 Grenoble 9, France.
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MeSH Terms
Descriptor/Qualifier:
Adenosine / analysis
Biophysics / methods*
DNA, Single-Stranded / analysis*
Models, Statistical
Normal Distribution
Nucleic Acids / analysis*
Poly A / chemistry
Polymers / analysis
Temperature
Chemical
Reg. No./Substance:
0/DNA, Single-Stranded; 0/Nucleic Acids; 0/Polymers; 24937-83-5/Poly A; 25191-20-2/poly(dA); 30143-02-3/polyadenosine; 58-61-7/Adenosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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