| Effects of smoking on pulmonary uptake of technetium-99m methoxyisobutylisonitrile during myocardial perfusion imaging. | |
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MedLine Citation:
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PMID: 10070838 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: To determine the influence of smoking on 99mTc-labeled methoxyisobutylisonitrile (99mTc-MIBI) lung uptake during myocardial perfusion imaging, we examined 60 subjects with normal myocardial perfusion scans, normal coronary angiograms, and no evidence of left ventricular hypertrophy. METHODS AND RESULTS: The subjects were divided into 2 groups: Group 1 subjects had smoking histories of at least 10 pack-years and Group 2 subjects were nonsmokers. 99mTc-MIBI lung to heart ratios (L/H ratios) from anterior planar images were obtained for all subjects during exercise and resting states. 99mTc-MIBI L/H ratios in smokers were significantly higher than in nonsmokers in both exercise and resting states. However, no significant difference in L/H ratios was found between exercise and resting states in smokers and nonsmokers. In addition, no significant correlation was found between smoking pack-years and either rest or exercise L/H ratios. CONCLUSIONS: 99mTc-MIBI L/H ratios in smokers are higher than in nonsmokers. This must be considered when 99mTc-MIBI L/H ratios are used clinically. |
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Authors:
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C H Kao; Y Y Shen; J K Lee |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology Volume: 6 ISSN: 1071-3581 ISO Abbreviation: J Nucl Cardiol Publication Date: 1999 Jan-Feb |
Date Detail:
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Created Date: 1999-04-23 Completed Date: 1999-04-23 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9423534 Medline TA: J Nucl Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 29-32 Citation Subset: IM |
Affiliation:
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Department of Nuclear Medicine, Taichung Veterans General Hospital, Taiwan, Republic of China. kao@vghtc.vghtc.gov.tw |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Exercise Test Female Heart / radionuclide imaging* Humans Lung / radionuclide imaging* Male Middle Aged Radiopharmaceuticals / diagnostic use* Retrospective Studies Smoking* Technetium Tc 99m Sestamibi / diagnostic use* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 109581-73-9/Technetium Tc 99m Sestamibi |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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