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THE EFFECTS OF SERUM TREATED WITH AGAR.
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MedLine Citation:
PMID:  19868039     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The intravenous injection of horse serum, kept for 2 hours at 38 degrees C. in the presence of one-fifth of its volume of a suspension of 0.5 per cent agar in physiological salt solution and then separated from the agar by centrifugalization and filtration, produces in normal rabbits in adequate doses a considerable and prolonged fall in the blood pressure, expulsion of feces, a diminished coagulability in the carotid blood, and at times accelerated respiration; that is, the various symptoms observed after the intravenous injection of horse serum in a seroanaphylactized rabbit. Horse serum previously kept for 30 minutes at 56 degrees C. and then treated with agar in the manner described above, when injected intravenously into a normal rabbit will have no more effect on the arterial pressure, on the intestinal movement, on the respiratory rate, or the coagulation of arterial blood than the introduction of horse serum into the veins of a normal rabbit.
Authors:
E Zunz; M Gelat
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of experimental medicine     Volume:  24     ISSN:  0022-1007     ISO Abbreviation:  J. Exp. Med.     Publication Date:  1916 Sep 
Date Detail:
Created Date:  2010-06-23     Completed Date:  2010-06-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985109R     Medline TA:  J Exp Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  247-69     Citation Subset:  -    
Affiliation:
Laboratories of the Physiological Institute of the University of Lausanne, Lausanne, Switzerland.
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Full Text
Journal Information
Journal ID (nlm-ta): J Exp Med
ISSN: 0022-1007
ISSN: 1540-9538
Publisher: The Rockefeller University Press
Article Information
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Copyright © Copyright, 1916, by The Rockefeller Institute for Medical Research New York
Received Day: 27 Month: 3 Year: 1916
Print publication date: Day: 1 Month: 9 Year: 1916
Volume: 24 Issue: 3
First Page: 247 Last Page: 269
ID: 2125407
PubMed Id: 19868039

THE EFFECTS OF SERUM TREATED WITH AGAR
Edgard Zunz
Maurice Gelat
From the Laboratories of the Physiological Institute of the University of Lausanne, Lausanne, Switzerland.


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