Document Detail

Effects of selenium and vitamin E on incidence of retained placenta.
MedLine Citation:
PMID:  4044976     Owner:  NLM     Status:  MEDLINE    
In a series of experiments over 3 yr, relatively low doses of selenium and vitamin E were injected intramuscularly 3 wk prepartum to pregnant Israeli-Holstein dairy cows in a high-producing herd (9000 kg milk/yr) with a history of retained placenta in 17% of the primiparous and 28% of the multiparous animals, as recorded for the 12 mo preceding the study. Selenium ranged from .035 to .109 ppm in the prepartum diet and from .160 to .200 ppm in the postpartum diet. Doses of selenium ranging from 2.3 to 23.0 mg reduced the incidence of retained placenta in 186 primiparous and in 428 multiparous to 7 and 15%, which was half of that of controls. Low doses of selenium (2.3 to 4.6 mg) tended to be more effective than higher ones. Selenium alone was at least as effective as a combination of selenium and vitamin E. Dosage, timing, mechanism, and interactions of selenium with other factors in reducing the incidence of retained placenta need clarification.
S Eger; D Drori; I Kadoori; N Miller; H Schindler
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of dairy science     Volume:  68     ISSN:  0022-0302     ISO Abbreviation:  J. Dairy Sci.     Publication Date:  1985 Aug 
Date Detail:
Created Date:  1985-11-20     Completed Date:  1985-11-20     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  2985126R     Medline TA:  J Dairy Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2119-22     Citation Subset:  IM    
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MeSH Terms
Cattle Diseases / prevention & control*
Dose-Response Relationship, Drug
Injections, Intramuscular / veterinary
Obstetric Labor Complications / prevention & control,  veterinary*
Placenta Accreta / prevention & control,  veterinary*
Selenious Acid
Selenium / administration & dosage,  therapeutic use*
Vitamin E / administration & dosage,  analogs & derivatives*,  therapeutic use
alpha-Tocopherol* / analogs & derivatives*
Reg. No./Substance:
1406-18-4/Vitamin E; 1406-66-2/Tocopherols; 59-02-9/alpha-Tocopherol; 7782-49-2/Selenium; 7783-00-8/Selenious Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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