Document Detail

Effects of selective blood and tissue heating on blood flow in the dog hindlimb.
MedLine Citation:
PMID:  1972027     Owner:  NLM     Status:  MEDLINE    
This study investigated the effects of independent and combined heating of blood and tissue to 40-44 degrees C on femoral blood flow in the hindlimb of the anaesthetized dog. An increase in arterial blood temperature by means of an extracorporeal circuit increased femoral vascular resistance. An increase in limb tissue temperature, induced by external hot packs, decreased femoral vascular resistance. These responses occurred both before and after sympathetic blockade. Neither blood heating nor tissue heating affected the hyperaemic response to exercise. When blood and tissue heating were combined, femoral vascular resistance remained unaffected. We conclude that changes in blood temperature do not contribute to the hyperaemic effect of limb warming and that exercise combined with limb warming is no more effective as a therapeutic tool for promoting limb flow than exercise alone.
J M McMeeken; C Bell
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Experimental physiology     Volume:  75     ISSN:  0958-0670     ISO Abbreviation:  Exp. Physiol.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-07-17     Completed Date:  1990-07-17     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9002940     Medline TA:  Exp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  359-66     Citation Subset:  IM    
Department of Physiology, University of Melbourne Medical Centre, Victoria, Australia.
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MeSH Terms
Blood Flow Velocity / drug effects
Blood Pressure / drug effects,  physiology
Body Temperature
Femoral Artery*
Heart Rate / drug effects,  physiology
Hexamethonium Compounds / diagnostic use
Hindlimb / blood supply
Hyperthermia, Induced*
Physical Exertion / physiology
Skin Temperature
Reg. No./Substance:
0/Hexamethonium Compounds; 60-26-4/Hexamethonium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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