Document Detail

Effects of sedation with acepromazine on echocardiographic measurements in eight healthy thoroughbred horses.
MedLine Citation:
PMID:  18603631     Owner:  NLM     Status:  MEDLINE    
Eight normal thoroughbred horses were examined by echocardiography before and 10 minutes after they had been sedated by the intravenous administration of 0.03 mg/kg acepromazine. There were significant (P<0.025) increases in the diameters of the pulmonary artery and the aorta, measured at end-systole, and in the thickness of the interventricular septum, measured at end-systole and end-diastole. In addition, there was a significant (P<0.001) decrease in the diameter of the left atrium measured at end-diastole. The remaining cardiac dimensions, all the indices of cardiac function, and the occurrence and severity of valvular regurgitation were not affected by sedation.
N J Menzies-Gow
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The Veterinary record     Volume:  163     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-07-08     Completed Date:  2008-11-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  England    
Other Details:
Languages:  eng     Pagination:  21-5     Citation Subset:  IM    
Department of Veterinary Clinical Sciences, Royal Veterinary College, Hawkshead Lane, Hatfield AL9 7TA, UK.
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MeSH Terms
Acepromazine / pharmacology*
Echocardiography / drug effects,  veterinary*
Heart / anatomy & histology
Hypnotics and Sedatives / pharmacology*
Reg. No./Substance:
0/Hypnotics and Sedatives; 61-00-7/Acepromazine

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