Document Detail

Effects of ribose as an ergogenic aid.
MedLine Citation:
PMID:  16937963     Owner:  NLM     Status:  MEDLINE    
The amount of adenosine triphosphate (ATP) stored in the muscle available for immediate use is limited, and once used, must be resynthesized in the muscle. Ribose, a naturally occurring pentose sugar, helps resynthesize ATP for use in muscles. There have been claims that ribose supplements increase ATP levels and improve performance. Other studies have provided mixed results on the effectiveness of ribose as an ergogenic aid at high doses. None of these studies have compared the impact of the recommended dose of ribose on athletes and nonathletes under exercise conditions that are most conducive for effectiveness. The purpose of this study was to evaluate the effectiveness of ribose as an ergogenic aid at the dose recommended for supplements currently on the market during an exercise trial to maximize its efficacy. Male subjects (n = 11) performed 2 trials 1 week apart. Each trial consisted of three 30-second Wingate tests with a 2-minute recovery between each test. Trials were counterbalanced, with 1 trial being performed with 625 mg of ribose and the other with a placebo. Peak power, mean power, and percent decrease in power were recorded during each Wingate test. Repeated-measures analysis of variance (p > 0.05) found no significant differences between ribose and placebo. These results suggest that ribose had no effect on performance when taken orally, at the dose suggested by the distributor.
Willard W Peveler; Phillip A Bishop; Ed J Whitehorn
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of strength and conditioning research / National Strength & Conditioning Association     Volume:  20     ISSN:  1064-8011     ISO Abbreviation:  J Strength Cond Res     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-29     Completed Date:  2006-12-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9415084     Medline TA:  J Strength Cond Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  519-22     Citation Subset:  IM; S    
Department of Health and Kinesiology, Mississippi University for Women, Columbus, MS 39701, USA.
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MeSH Terms
Analysis of Variance
Bicycling / physiology*
Cross-Over Studies
Dietary Supplements*
Double-Blind Method
Exercise Test
Physical Endurance / drug effects*,  physiology
Physical Fitness / physiology
Ribose / pharmacology*
Weight Lifting / physiology
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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