| Effects of restricted feeding on blood parameters in pregnant rabbits. | |
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MedLine Citation:
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PMID: 19182443 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The effects of restricted feeding (20 g/day from gestational day (GD) 6 to 28) on pregnancy outcome and blood parameters were examined in pregnant rabbits. As compared with the group which was allowed free access to diet throughout the gestational period (NT group), the group subjected to restricted feeding (R group) showed significantly lower values in many parameters such as total protein, albumin and triglyceride on GDs 22 and 28, reflecting low nutritive conditions. In addition, there were significant changes in blood coagulation-related parameters, suggesting an imbalance between coagulation and anti-coagulation factors. Moreover, abortions occurred in about half of the animals of the R group between GDs 23 and 27. When aborted rabbits were compared with those which could maintain pregnancy under restricted feeding, total protein, albumin, platelets and antithrombin III values and especially blood progesterone concentration were significantly lower in aborted rabbits on GD 22, prior to occurrence of abortion. These results suggested that abortions due to restricted feeding might be brought about by lower nutritive conditions, an imbalance of blood coagulation-related factors and lower blood progesterone concentrations. |
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Authors:
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Tetsuya Matsuoka; Hiroyasu Mizuguchi; Yasumoto Mizoguchi; Takako Endho; Ryo Kamata; Kazuya Fukuda; Tsutomu Ishikawa; Yuzo Asano |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Journal of toxicological sciences Volume: 34 ISSN: 1880-3989 ISO Abbreviation: J Toxicol Sci Publication Date: 2009 Feb |
Date Detail:
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Created Date: 2009-02-02 Completed Date: 2009-05-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7805798 Medline TA: J Toxicol Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 129-37 Citation Subset: IM |
Affiliation:
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Kannami Laboratory, Bozo Research Center Inc., Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Veterinary
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blood Animals Blood Chemical Analysis / methods*, statistics & numerical data Blood Coagulation / physiology Blood Coagulation Factors / analysis Blood Coagulation Tests / methods, statistics & numerical data Cesarean Section / veterinary Female Food Deprivation* Gestational Age Pregnancy Pregnancy Outcome Pregnancy, Animal / blood* Progesterone / blood Rabbits Time Factors Weight Gain Weight Loss |
| Chemical | |
Reg. No./Substance:
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0/Blood Coagulation Factors; 57-83-0/Progesterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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