| Effects of respiratory liver motion on heating for gated and model-based motion-compensated high-intensity focused ultrasound ablation. | |
MedLine Citation:
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PMID: 22003668 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PURPOSE: To quantify the effects of respiratory motion on high-intensity focused ultrasound heating of liver tissue by comparing the simulated ablation using a conventional respiratory gating versus a MR-model-based motion compensation approach. METHODS: To measure liver motion, dynamic free-breathing abdominal MR scans were acquired for five volunteers. Deformable registration was used to calculate continuous motion models, and tissue heating at a moving single focus was computed in 3-D by solving the bioheat equation. Ablated volume ratios with respect to the static case, V(ab), were determined for a range of exposure times t(exp) and heating rates r. RESULTS: To achieve V(ab) > 90% required t(exp) < 0.5s and r > 120 degrees C/s when gating, whereas t(exp) < 1s and r > 60 degrees C/s for motion-compensation. CONCLUSIONS: Accurate compensation for respiratory motion is important for efficient tissue ablation. Model-based motion compensation allows substantially lower heating rates than gating, reducing the risk of skin burns and focal boiling. |
Authors:
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Erik-Jan Rijkhorst; Ian Rivens; Gail ter Haar; David Hawkes; Dean Barratt |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention Volume: 14 ISSN: - ISO Abbreviation: Med Image Comput Comput Assist Interv Publication Date: 2011 |
Date Detail:
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Created Date: 2011-10-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101249582 Medline TA: Med Image Comput Comput Assist Interv Country: Germany |
Other Details:
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Languages: eng Pagination: 605-12 Citation Subset: IM |
Affiliation:
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Centre for Medical Image Computing, University College London, London, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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