Document Detail

Effects of regular and decaffeinated coffee on fetal breathing and heart rate.
MedLine Citation:
PMID:  2729379     Owner:  NLM     Status:  MEDLINE    
The effects of maternal consumption of regular or decaffeinated coffee on the fetus were determined in eight pregnant women at 32 to 36 weeks of gestation. This was a single-blind crossover study in which two cups of caffeinated or decaffeinated coffee were consumed after an overnight fast. The total maternal caffeine ingested was 454 +/- 4 mg for regular coffee and 12 +/- 0.4 mg for decaffeinated coffee. Maternal consumption of regular coffee was associated with a twofold increase in the incidence of fetal breathing activity and a significant fall in baseline fetal heart rate. Decaffeinated coffee also increased the incidence of fetal breathing activity and produced a slight reduction in fetal heart rate. These results indicate that maternal consumption of regular and decaffeinated coffee can stimulate fetal breathing. Moreover, these results suggest that caffeinated coffee can produce baseline shifts in fetal heart rate.
H S Salvador; B J Koos
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  160     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1989 May 
Date Detail:
Created Date:  1989-06-27     Completed Date:  1989-06-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1043-7     Citation Subset:  AIM; IM    
Department of Gynecology and Obstetrics, School of Medicine, Loma Linda University, CA 92354.
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MeSH Terms
Blood Glucose / analysis
Blood Pressure / drug effects
Caffeine / adverse effects*,  blood
Catecholamines / blood
Coffee / adverse effects*
Fetal Monitoring
Fetal Movement / drug effects*
Heart Rate / drug effects
Heart Rate, Fetal / drug effects*
Pregnancy Trimester, Third
Respiration / drug effects*
Time Factors
Grant Support
Reg. No./Substance:
0/Blood Glucose; 0/Catecholamines; 0/Coffee; 58-08-2/Caffeine
Erratum In:
Am J Obstet Gynecol 1989 Sep;161(3):669

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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