Document Detail

Effects of quetiapine extended release on sleep and quality of life in midlife women with major depressive disorder.
MedLine Citation:
PMID:  23143411     Owner:  NLM     Status:  Publisher    
Depression during midlife years may lead to significant sleep disturbances and adversely impact quality of life (QOL). In this report, we examined the effects of treatment with quetiapine extended release (XR), 150-300 mg/day, on sleep and QOL in 23 midlife women with major depressive disorder (MDD). Quetiapine XR improved subjective sleep distress, overall sleep parameters, and sleep-related QOL, ultimately leading to significant improvement in menopause-related QOL. While larger, controlled trials are still awaited, these preliminary results are encouraging and suggest that quetiapine XR may be a useful tool in treating symptomatic midlife women with MDD.
Benicio N Frey; Erika Haber; Gustavo C D Mendes; Meir Steiner; Claudio N Soares
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-11
Journal Detail:
Title:  Archives of women's mental health     Volume:  -     ISSN:  1435-1102     ISO Abbreviation:  Arch Womens Ment Health     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9815663     Medline TA:  Arch Womens Ment Health     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Women's Health Concerns Clinic, 301 James St South, Suite FB638, L8P 3B6, Hamilton, Ontario, Canada.
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