Document Detail


Effects on pulmonary function of daily exposure to dry or humidified hyperbaric oxygen.
MedLine Citation:
PMID:  9241693     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to examine the effects of breathing dry or humidified hyperbaric oxygen on pulmonary function. Pulmonary function tests were performed before and after each of 10 hyperbaric oxygen exposures at 2.5 atmospheres absolute (ATA) for 95 min in a group of 13 patients treated daily by hyperbaric oxygen for problem wounds. Patients breathed dry oxygen during five successive sessions and humidified oxygen during the remaining five. No differences were found between forced vital capacities (FVC) and maximal expiratory flows before and after hyperbaric oxygen exposure while breathing dry or humidified oxygen. Significant differences were found for the changes in the percentage of FVC expired in 1 s (FEV1%) and mean forced mid-expiratory flow rate during the middle half of the FVC (FEF25-75%) on day 1 alone: decrements of 1.42 and 2.96%, respectively, under dry oxygen, vs. increments of 3.93 and 34.4%, respectively, for humidified oxygen. Day-to-day decrements in the percent changes in FEV1% and FEF25-75% were observed while breathing humidified hyperbaric oxygen. These results demonstrate that repeated daily exposure to humidified hyperbaric oxygen abolishes the initial beneficial effect of humidification on peripheral airways flow characteristics.
Authors:
A Shupak; A Abramovich; Y Adir; I Goldenberg; Y Ramon; P Halpern; A Ariel
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Respiration physiology     Volume:  108     ISSN:  0034-5687     ISO Abbreviation:  Respir Physiol     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-09-11     Completed Date:  1997-09-11     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0047142     Medline TA:  Respir Physiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  241-6     Citation Subset:  IM    
Affiliation:
Israel Naval Medical Institute, IDF Medical Corps, Haifa, Israel.
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MeSH Terms
Descriptor/Qualifier:
Adult
Humans
Humidity*
Hyperbaric Oxygenation*
Maximal Expiratory Flow Rate
Maximal Midexpiratory Flow Rate
Middle Aged
Respiratory Function Tests
Respiratory Mechanics*
Vital Capacity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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