| Effects of puff number and puff spacing on carbon monoxide exposure from commercial brand cigarettes. | |
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MedLine Citation:
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PMID: 2616605 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Six chronic smokers of mid- to high-carbon monoxide (CO) yield cigarettes smoked ultralow- (1.6 mg CO), low- (5.9 mg CO) and high- (14.3 mg CO) yield commercial cigarettes under controlled smoking conditions in which either puff number or puff spacing was manipulated. CO exposure (pre- to postsmoking increments) was directly related to the number of puffs taken for all cigarette yields. CO exposure from the high- and low-yield cigarettes was equivalent when the number of puffs taken from the low-yield cigarettes was increased by 50% (from 8 to 12 puffs). In contrast, CO exposure from ultralow-yield cigarettes was still marginally lower than exposure from high-yield cigarettes after a 4-fold increase in puff number (8 to 32 puffs). Puff spacing did not affect biological exposure to CO. The study showed that the number of puffs taken during smoking can clearly affect biological exposure to CO, but that compensation for lowered yield using increased puffs is much more difficult when ultralow- as compared with low or "light"- yield cigarettes are smoked. |
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Authors:
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L L Weinhold; M L Stitzer |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Pharmacology, biochemistry, and behavior Volume: 33 ISSN: 0091-3057 ISO Abbreviation: Pharmacol. Biochem. Behav. Publication Date: 1989 Aug |
Date Detail:
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Created Date: 1990-03-06 Completed Date: 1990-03-06 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0367050 Medline TA: Pharmacol Biochem Behav Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 853-8 Citation Subset: IM |
Affiliation:
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Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21224. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Breath Tests* Carbon Monoxide / analysis* Environmental Exposure Female Humans Male Middle Aged Respiratory Function Tests Smoking* Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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5 R01 CA 37736/CA/NCI NIH HHS; T 32 DA 07209/DA/NIDA NIH HHS |
| Chemical | |
Reg. No./Substance:
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630-08-0/Carbon Monoxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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