Document Detail

Effects of protein deficiency on plasma levels of 25-hydroxyvitamin and 24,25-dihydroxyvitamin D in the rat.
MedLine Citation:
PMID:  6968507     Owner:  NLM     Status:  MEDLINE    
The effect of protein deficiency on plasma 25-hydroxyvitamin and 24,25-dihydroxyvitamin D concentrations was determined in weanling rats. The concentrations of these metabolites did not differ in rats fed diet providing either 0.5 or 21% casein for 4 weeks postweaning. Also, no change was observed in plasma levels of these metabolites in rats fed the 21% casein diet in amounts restricted to those consumed by the 0.5% casein animals for the same period of time. The results indicate that the synthesis and transport of 25-hydroxyvitamin and 24,25-dihydroxyvitamin D are not significantly affected by either a protein deficiency or a total food striction during the early postweaning period. This finding may be relevant to the vitamin D status of children with kwashiorkor.
D J Philbrick; B W Hollis; H H Draper
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  33     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1980 Oct 
Date Detail:
Created Date:  1980-12-16     Completed Date:  1980-12-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2174-6     Citation Subset:  AIM; IM    
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MeSH Terms
24,25-Dihydroxyvitamin D 3
25-Hydroxyvitamin D 2
Caseins / administration & dosage
Dihydroxycholecalciferols / blood*
Hydroxycholecalciferols / blood*
Protein Deficiency / metabolism*
Reg. No./Substance:
0/Caseins; 0/Dihydroxycholecalciferols; 0/Hydroxycholecalciferols; 21343-40-8/25-Hydroxyvitamin D 2; 40013-87-4/24,25-Dihydroxyvitamin D 3

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