| Effects of prolonging administration gonadotropin on unexpectedly poor ovarian responders undergoing in vitro fertilization. | |
| | |
MedLine Citation:
|
PMID: 20236519 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: There are still some patients who show poor response to ovarian stimulation prior to evidence of normal ovarian reserve in vitro fertilization. However, there are few studies about how to treat the unexpectedly ovarian poor responder in vitro fertilization. The main aim of this study evaluate the effect of prolonging administration follicle-stimulating hormone in woman with the unexpectedly ovarian poor responder in vitro fertilization on implantation rate, clinical pregnancy rate and live birth rate. METHODS: 922 patients subjected to IVF were divided into two groups according to the predicted criterion of ovarian poor response. 116 patients predicted poor response received the short protocol (group C). The others received the long protocol, among the latter, there were 149 patients undergoing unexpectedly ovarian poor response (group B) and 657 patients exhibited normal ovarian response (group A). The doses of gonadotropin, duration of administration, implantation rate, clinical pregnancy rate and live birth rate were recorded among three groups. RESULTS: The implantation rate of embryo, clinic pregnancy rate and delivery rate are similar between the group A and group B, while there are significant differences between the doses of gonadotropins (35.1 +/- 8.9 ampules vs.53.0 +/- 15.9 ampules) and the duration of administration (15.3 +/- 3.6D vs. 9.8 +/- 2.6D) of these two groups. There are no significant differences about clinical pregnancy rate and live birth rate between group B and group C. CONCLUSION: Prolonging administration gonadotropin on the unexpectedly poor ovarian responders does not lower live birth rate in vitro fertilization. |
| | |
Authors:
|
Zhaolian Wei; Xianxia Cheng; Huirong Li; Yunxia Cao; Lin Cong; Ping Zhou; Jun Li |
Related Documents
:
|
18950959 - "exterritorial" lymphocytic hypophysitis within an ovarian teratoma during pregnancy: a... 15730409 - Polycystic ovarian syndrome: marked differences between endocrinologists and gynaecolog... 724179 - Ovarian pregnancy associated with copper-7 intrauterine device. 14707749 - Nonobstetric surgery during pregnancy: what are the risks of anesthesia? 10086669 - Effect of cisapride on secondary peristalsis in patients with gastroesophageal reflux d... 18588619 - Primary ovarian pregnancy after the empty follicle syndrome: a case report. 720059 - Pregnant mare's serum gonadotropin: v. indomethacin or cortisone and the reversal of an... 18394189 - Valsalva retinopathy in pregnancy: a case report. 8545259 - Somatostatin levels during infancy, pregnancy, and lactation: a review. |
Publication Detail:
|
Type: Comparative Study; Evaluation Studies; Journal Article Date: 2010-03-17 |
Journal Detail:
|
Title: Reproductive biology and endocrinology : RB&E Volume: 8 ISSN: 1477-7827 ISO Abbreviation: Reprod. Biol. Endocrinol. Publication Date: 2010 |
Date Detail:
|
Created Date: 2010-03-25 Completed Date: 2010-05-06 Revised Date: 2010-09-30 |
Medline Journal Info:
|
Nlm Unique ID: 101153627 Medline TA: Reprod Biol Endocrinol Country: England |
Other Details:
|
Languages: eng Pagination: 26 Citation Subset: IM |
Affiliation:
|
Reproductive Medicine Center, The First Affiliated Hospital, Anhui Medical University, Hefei, 230022, PR China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Dose-Response Relationship, Drug Drug Administration Schedule Female Fertility Agents, Female / administration & dosage Fertilization in Vitro* Follicle Stimulating Hormone, Human / administration & dosage Gonadotropins / administration & dosage* Humans Infertility / diagnosis, therapy* Leuprolide / administration & dosage Ovulation Induction / methods* Pregnancy Pregnancy Rate Retrospective Studies Time Factors Treatment Failure Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
0/Fertility Agents, Female; 0/Follicle Stimulating Hormone, Human; 0/Gonadotropins; 53714-56-0/Leuprolide |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosop...
Next Document: An optimized TOPS+ comparison method for enhanced TOPS models.