Document Detail


Effects of pressure on the phase transition of bilayers in liposomes. Influence of cholesterol and alpha-tocopherol.
MedLine Citation:
PMID:  6722277     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of pressure on the gel-to-liquid crystalline phase transition temperature of dimyristoylphosphatidylcholine (DMPC) bilayers containing cholesterol, alpha-tocopherol, and alpha-tocopheryl acetate were studied by fluorescence depolarization. The transition temperature of cholesterol mixtures (greater than 7.5 mol%) was lower than that of 100% DMPC at atmospheric pressure, but it became higher than the latter on increase in pressure. The thermodynamic parameters of the transition (delta V, delta S, delta H) were estimated and the functions of cholesterol and alpha-tocopherols in the bilayers are discussed.
Authors:
K Tamura; Y Higashi; K Wazumi; A Suzuki
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Biophysical chemistry     Volume:  19     ISSN:  0301-4622     ISO Abbreviation:  Biophys. Chem.     Publication Date:  1984 May 
Date Detail:
Created Date:  1984-07-25     Completed Date:  1984-07-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0403171     Medline TA:  Biophys Chem     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  273-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cholesterol*
Dimyristoylphosphatidylcholine*
Lipid Bilayers*
Models, Biological
Molecular Conformation
Thermodynamics
Tocopherols
Vitamin E* / analogs & derivatives
alpha-Tocopherol* / analogs & derivatives*
Chemical
Reg. No./Substance:
0/Lipid Bilayers; 13699-48-4/Dimyristoylphosphatidylcholine; 1406-18-4/Vitamin E; 1406-66-2/Tocopherols; 57-88-5/Cholesterol; 59-02-9/alpha-Tocopherol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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