Document Detail

Effects of prenatal malnutrition on development of oral tissue in neonatal rats.
MedLine Citation:
PMID:  6814349     Owner:  NLM     Status:  MEDLINE    
The effects of prenatal malnutrition on the growth of incisor and molar tooth germs and tongue were investigated in newborn rats. Compared with the results on the young of well-nourished mothers, the young of the malnourished animals had fewer and smaller cells in the molar tooth germs and fewer cells in incisor tooth germs. The tongue of the malnourished animals had fewer but larger cells. 45Ca uptake studies and alkaline and acid phosphatase activities suggested that prenatal malnutrition affected incisor and molar tooth germs in different ways. Alkaline phosphatase activity in the tongue did not differ between dietary groups. The results indicate that an adequate protein intake is extremely important for the healthy development of the teeth and tongue of the offspring.
M M Winkler; T Nakamoto
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of nutrition & metabolism     Volume:  26     ISSN:  0250-6807     ISO Abbreviation:  Ann. Nutr. Metab.     Publication Date:  1982  
Date Detail:
Created Date:  1982-12-16     Completed Date:  1982-12-16     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8105511     Medline TA:  Ann Nutr Metab     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  248-53     Citation Subset:  IM    
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MeSH Terms
Acid Phosphatase / metabolism
Alkaline Phosphatase / metabolism
Animals, Newborn
Calcium / metabolism
Incisor / growth & development*
Molar / growth & development*
Placental Insufficiency / physiopathology
Pregnancy Complications / physiopathology*
Protein-Energy Malnutrition / physiopathology*
Rats, Inbred Strains
Tongue / growth & development*,  metabolism
Tooth Germ / growth & development*,  metabolism
Reg. No./Substance:
7440-70-2/Calcium; EC Phosphatase; EC Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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