Document Detail

Effects of prenatal alcohol exposure on rat pups' ability to elicit retrieval behavior from dams.
MedLine Citation:
PMID:  2340959     Owner:  NLM     Status:  MEDLINE    
Research on fetal alcohol syndrome (FAS) has historically held that postnatal deficits result directly from prenatal alcohol exposure. Such exposure may alter infant behavior, and this in turn may affect maternal responsiveness and consequently increase the infant's risk for postnatal deficits. This study examined the effect of prenatal alcohol exposure on postnatal blood ethanol concentrations, pup development, and the ability of pups to elicit retrieval behaviors from the dam. Dams given access to a 15% ethanol solution throughout gestation and lactation showed blood ethanol concentrations of 0.1%, whereas their pups had concentrations below the sensitivity of the test. Prenatal alcohol exposure was shown to have pharmacological effects on the pup's righting reflex and nutritional effects on its rate of weight gain. Control pups were better able to elicit retrieval behavior from control and alcoholic dams than were fetally alcoholic pups. These results indicate that the condition of the pup can influence maternal responsiveness which, in turn, can influence pup development.
J W Ness; J J Franchina
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Developmental psychobiology     Volume:  23     ISSN:  0012-1630     ISO Abbreviation:  Dev Psychobiol     Publication Date:  1990 Jan 
Date Detail:
Created Date:  1990-06-27     Completed Date:  1990-06-27     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0164074     Medline TA:  Dev Psychobiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  85-99     Citation Subset:  IM    
Department of Psychology, Virginia Polytechnic Institute and State University, Blacksburg.
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MeSH Terms
Arousal* / physiology
Ethanol / pharmacokinetics
Fetal Alcohol Syndrome / blood,  psychology*
Maternal Behavior*
Maternal-Fetal Exchange / physiology
Rats, Inbred Strains
Reaction Time / physiology
Vocalization, Animal / physiology
Reg. No./Substance:

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