Document Detail


Effects of pregnancy on the febrile responses in sheep.
MedLine Citation:
PMID:  6910716     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pyrogens were injected into unshorn pregnant and non-pregnant Soay and Clun Forest sheep and the effects on rectal temperature and thermoregulatory mechanisms monitored. Plasma concentrations of unconjugated oestrogens, progesterone and cortisol were measured in the sheep tested in late pregnancy. The effect of pyrogens was also examined in ovariectomized ewes treated with oestrogen and with oestrogen plus progesterone. In contrast to reports of work on shorn sheep all sheep developed a fever even when close to term but the increase in peripheral vasomotor tone normally induced by pyrogens was attenuated in the pregnant Clun Forest ewes. The hormone-treated ovariectomized animals developed normal fevers and provided little indication of a possible relation between peripheral levels of ovarian steroids and the degree of fever. The question of whether an endogenous antipyretic substance is present in pregnant sheep is discussed.
Authors:
R B Heap; A Silver; D E Walters
Related Documents :
6868176 - Hyperbaric exposure during pregnancy in sheep: staged and rapid decompression.
3301776 - The crossbred sire: experimental results for sheep.
8722286 - Winter poisoning of coyotes and raptors with furadan-laced carcass baits.
6713736 - Presence and stability of gastrin in the gastric juice of the fetal sheep.
25040556 - Should the individual preterm birth risk be incorporated into the embryo transfer polic...
11241536 - Use of the kleihauer test to detect fetal erythroblasts in the maternal circulation.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Quarterly journal of experimental physiology (Cambridge, England)     Volume:  66     ISSN:  0144-8757     ISO Abbreviation:  Q J Exp Physiol     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-09-15     Completed Date:  1981-09-15     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8206873     Medline TA:  Q J Exp Physiol     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  129-44     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Estrogens / blood
Female
Fever / chemically induced,  veterinary*
Hydrocortisone / blood
Pregnancy
Pregnancy, Animal*
Progesterone / blood
Pyrogens / administration & dosage*
Sheep / physiology*
Chemical
Reg. No./Substance:
0/Estrogens; 0/Pyrogens; 50-23-7/Hydrocortisone; 57-83-0/Progesterone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The influence of high and low sodium intake on blood volume in the dog.
Next Document:  A horseradish peroxidase study of vagal motoneurones with axons in cardiac and pulmonary branches of...