Document Detail

Effects of polyunsaturated fatty acids on cocaine-conditioned place preference in mice.
MedLine Citation:
PMID:  22390908     Owner:  NLM     Status:  Publisher    
OBJECTIVE: The objective of the present study was to assess whether the administration of polyunsaturated fatty acids (PUFAs) would lead to alterations in cocaine-conditioned place preference by correlating behavioral data and plasma levels of PUFAs. METHODS: Five groups of C57Bl/6J mice received a linseed oil supplement or a control solution for 19 days and were conditioned to cocaine. RESULTS: PUFAs did not exert a protective effect against cocaine-conditioned place-preference behavior, although there were significant differences in the levels of eicosapentaenoic acid (EPA) and linoleic acid among the groups tested. Higher doses of PUFAs might be necessary to induce a change in the plasma level of EPA in cocaine-conditioned mice. DISCUSSION: PUFAs had no effect on cocaine-conditioned place preference.
Eserian Jaqueline Kalleian; D'Almeida Vânia; Andersen Monica Levy; Galduróz José Carlos Fernandes
Related Documents :
3711588 - A method for the identification of sulfated glycopeptide by two-dimensional electrophor...
4250138 - Studies on the incorporation of (u-14c)glucose and (35s)sulphate into the acid glycosam...
18472058 - Biorejuvenation: theory and practice.
1320278 - In vivo evaluation of photoprotection against chronic ultraviolet-a irradiation by a ne...
21822658 - Enzymatic synthesizing of phytosterol oleic esters.
3143708 - Bioavailability of lysine in l-lysine.hcl.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-16
Journal Detail:
Title:  Nutritional neuroscience     Volume:  -     ISSN:  1476-8305     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-3-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100892202     Medline TA:  Nutr Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Nursing Home Deficiency Citations for Physical Restraints and Restrictive Side Rails.
Next Document:  Cardiovascular risk in relation to functionality of sequence variants in the gene coding for the low...