Document Detail


Effects of pleural fluid and positive end-expiratory pressure on the measurement of extravascular lung water by the double-indicator dilution technique.
MedLine Citation:
PMID:  1785234     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The reliability of the double-indicator dilution technique (dye/cold) for measuring extravascular lung water (EVLW) has been studied in lung-healthy dogs after pleural fluid injection of saline (up to 20 ml/kg) during mechanical ventilation at zero and 10 cmH2O (1.0 kPa) end-expiratory pressure (ZEEP and PEEP, respectively). Pleural fluid injection had no effect on EVLW at either ZEEP or PEEP. PEEP induced changes in cardiac output, and reduced both the intravascular (dye) and the thermal indicator volumes, but with no effect on the calculated EVLW. It is concluded that pleural fluid up to 20 ml/kg and ventilation with PEEP of 10 cmH2O (1.0 kPa) do not affect the reliability of the double-indicator dilution technique for measuring extravascular lung water in the dog.
Authors:
H Blomqvist; C J Wickerts; P G Rösblad
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  35     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  1991 Oct 
Date Detail:
Created Date:  1992-03-16     Completed Date:  1992-03-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  578-83     Citation Subset:  IM    
Affiliation:
Department of Anaesthesia and Intensive Care, Danderyd University Hospital, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs
Extravascular Lung Water / physiology*
Indicator Dilution Techniques
Pleural Effusion / physiopathology*
Positive-Pressure Respiration*

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