Document Detail


Effects of pistachio nuts consumption on plasma lipid profile and oxidative status in healthy volunteers.
MedLine Citation:
PMID:  16580587     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND AIM: Effects of pistachio nuts consumption on plasma lipid profile and oxidative status were investigated in healthy volunteers with normal lipid levels. METHODS AND RESULTS: The study was conducted in 24 healthy men and 20 healthy women. All subjects consumed their regular diets during a 1-week period. After this period, half of the subjects (12 men and 10 women, mean age 32.8 +/- 6.7 years) were randomized to a regular diet group and the other half (12 men and 10 women, mean age 33.4 +/- 7.2 years) were randomized to a pistachio group which involved substituting pistachio nuts for 20% of their daily caloric intake for 3 weeks. Plasma total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglyceride, malondialdehyde (MDA) and antioxidant potential (AOP) were measured before and after the dietary modification from all the subjects. After 3 weeks, with the pistachio diet, the mean plasma total cholesterol, MDA levels and, total cholesterol/HDL and LDL/HDL ratios were found to be significantly decreased (P < 0.05, P < 0.05, P < 0.001 and P < 0.01, respectively); on the contrary, HDL and AOP levels, and AOP/MDA ratios were significantly increased (P < 0.001, P < 0.05 and P < 0.01, respectively). Triglyceride and LDL levels also decreased but this was not statistically significant (P > 0.05). CONCLUSION: These results indicated that consumption of pistachio nuts decreased oxidative stress, and improved total cholesterol and HDL levels in healthy volunteers.
Authors:
A Kocyigit; A A Koylu; H Keles
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't     Date:  2006-02-09
Journal Detail:
Title:  Nutrition, metabolism, and cardiovascular diseases : NMCD     Volume:  16     ISSN:  0939-4753     ISO Abbreviation:  Nutr Metab Cardiovasc Dis     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-03     Completed Date:  2006-08-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9111474     Medline TA:  Nutr Metab Cardiovasc Dis     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  202-9     Citation Subset:  IM    
Affiliation:
Department of Clinical Biochemistry, Medical Faculty, Harran University, Sanliurfa, Turkey. kocyigit30@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Cholesterol / blood
Cholesterol, HDL / blood
Cholesterol, LDL / blood
Female
Humans
Lipid Metabolism / drug effects*
Lipids / blood*
Male
Malondialdehyde / blood
Oxidation-Reduction
Oxidative Stress / drug effects*
Pistacia* / chemistry
Triglycerides / blood
Chemical
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Lipids; 0/Triglycerides; 542-78-9/Malondialdehyde; 57-88-5/Cholesterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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