| Effects of physiologic human brain motion on proton spectroscopy: quantitative analysis and correction with cardiac gating. | |
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MedLine Citation:
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PMID: 11847046 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Summary: Proton MR spectroscopy is a powerful noninvasive method that enables measurement of certain brain metabolites in healthy subjects and patients with diseases. A major difficulty with clinical and research applications of in vivo proton MR spectroscopy is the variability of metabolite concentrations, especially in regions with substantial physiologic motion. In our preliminary evaluation, we tested the hypothesis that physiologic brain motion leads to lower mean metabolite concentrations and higher SDs for the measured metabolite concentrations. |
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Authors:
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Pradip M Pattany; Imad H Khamis; Brian C Bowen; Karl Goodkin; R Gregory Weaver; James B Murdoch; M Judith Donovon Post; Robert M Quencer |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: AJNR. American journal of neuroradiology Volume: 23 ISSN: 0195-6108 ISO Abbreviation: AJNR Am J Neuroradiol Publication Date: 2002 Feb |
Date Detail:
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Created Date: 2002-02-15 Completed Date: 2002-03-26 Revised Date: 2008-02-14 |
Medline Journal Info:
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Nlm Unique ID: 8003708 Medline TA: AJNR Am J Neuroradiol Country: United States |
Other Details:
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Languages: eng Pagination: 225-30 Citation Subset: IM |
Affiliation:
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Department of Radiology, University of Miami School of Medicine, 1115 NW 14th Street, Miami, FL 33136, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Body Water / metabolism Brain / metabolism* Humans Ion Channel Gating* Magnetic Resonance Imaging Magnetic Resonance Spectroscopy* Male Middle Aged Motion* Myocardium / metabolism* Prospective Studies |
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