Document Detail

Effects of physical training in intermittent claudication.
MedLine Citation:
PMID:  663544     Owner:  NLM     Status:  MEDLINE    
Mechanisms for increased claudication distance following physical training were studied in ten patients with peripheral arterial insufficiency. The exercise capacity on a bicycle ergometer increased by an average of 26% after 3--4 months of training (P less than 0.05). Neither maximum lower leg blood flow during the exercise test nor oxygen uptake at exhaustion changed significantly after training (-8% and +5%, respectively), whereas popliteal-venous O2-saturation was lower at exhaustion after the training than before (8.5 +/- 3.2 and 11.4 +/- 4.6, respectively, P less than 0.05). Anaerobic glycolysis, as evidenced by the lactate release, was also lowered after the training (P less than 0.05). In conclusion, the present study shows that the increased exercise capacity following physical training in claudicants is associated with an increased local aerobic working capacity despite a virtually unchanged blood flow. This increased aerobic exercise capacity might partly be explained by an increased O2 extraction in the lower leg during exercise.
D Sørlie; K Myhre
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Scandinavian journal of clinical and laboratory investigation     Volume:  38     ISSN:  0036-5513     ISO Abbreviation:  Scand. J. Clin. Lab. Invest.     Publication Date:  1978 May 
Date Detail:
Created Date:  1978-08-14     Completed Date:  1978-08-14     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0404375     Medline TA:  Scand J Clin Lab Invest     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  217-22     Citation Subset:  IM    
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MeSH Terms
Intermittent Claudication / rehabilitation*
Lactates / blood
Leg / blood supply
Middle Aged
Oxygen Consumption
Physical Education and Training*
Physical Exertion
Reg. No./Substance:

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