Document Detail


Effects of phosphate loading on metabolic and myocardial responses to maximal and endurance exercise.
MedLine Citation:
PMID:  1299483     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Six trained male cyclists and triathletes participated in a double blind study to determine the effects of phosphate loading on maximal and endurance exercise performance. Subjects ingested either 1 gm of tribasic sodium phosphate or a glucose placebo four times daily for 3 days prior to performing either an incremental maximal cycling test or a simulated 40-km time trial on a computerized race simulator. They continued the supplementation protocol for an additional day and then performed the remaining maximal or performance exercise test. Subjects observed a 17-day washout period between testing sessions and repeated the experiment with the alternate supplement regimen in identical fashion. Metabolic data were collected at 15-sec intervals while venous blood samples and 2D-echocardiographic data were collected during each stage of exercise during the maximal exercise test and at 8-km intervals during the 40-km time trial. Results indicate that phosphate loading attenuated anaerobic threshold, increased myocardial ejection fraction and fractional shortening, increased maximal oxidative capacity, and enhanced endurance performance in competitive cyclists and triathletes.
Authors:
R B Kreider; G W Miller; D Schenck; C W Cortes; V Miriel; C T Somma; P Rowland; C Turner; D Hill
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  International journal of sport nutrition     Volume:  2     ISSN:  1050-1606     ISO Abbreviation:  Int J Sport Nutr     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1993-05-20     Completed Date:  1993-05-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9307702     Medline TA:  Int J Sport Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  20-47     Citation Subset:  IM    
Affiliation:
Dept. of HPER, Old Dominion University, Norfolk, VA 23529-0196.
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MeSH Terms
Descriptor/Qualifier:
Adult
Bicycling
Double-Blind Method
Echocardiography
Exercise / physiology*
Heart / drug effects,  physiology*
Hematocrit
Hemodynamics
Hemoglobins / metabolism
Humans
Male
Metabolism / drug effects*
Oxygen Consumption
Phosphates / administration & dosage*,  blood,  pharmacology
Physical Endurance / physiology*
Placebos
Random Allocation
Chemical
Reg. No./Substance:
0/Hemoglobins; 0/Phosphates; 0/Placebos

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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