Document Detail

Effects of phentolamine on coronary blood flow in patients with recent myocardial infarction.
MedLine Citation:
PMID:  1148064     Owner:  NLM     Status:  MEDLINE    
The myocardial clearance of rubidium may be obtained by praecordial counting after intravenous injection of Rb-minus 86 Cl. Eight patients with recent myocardial infarction had this determination performed before and after the infusion of 10 mg phentolamine at a rate of 0.3 mg/minute. The average predrug myocardial clearance of Rb was 89.3 plus or minus 29.9 ml/min per 100 g myocardium. After phentolamine, the average myocardial clearance rose to 117.3 plus or minus 33.3 ml/min per 100 g myocardium (P LESS THAN 0.01). An explanation for this findings is presented as well as its possible clinical applications.
L Gould; C V Reddy; C J Blatt; R F Gomprecht; D B Hayt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  37     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1975 Jun 
Date Detail:
Created Date:  1975-11-01     Completed Date:  1975-11-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  647-51     Citation Subset:  AIM; IM    
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MeSH Terms
Coronary Circulation / drug effects*
Infusions, Parenteral
Injections, Intravenous
Middle Aged
Myocardial Infarction / drug therapy*
Myocardium / metabolism
Phentolamine / administration & dosage,  pharmacology,  therapeutic use*
Rubidium / metabolism
Reg. No./Substance:
0/Radioisotopes; 50-60-2/Phentolamine; 7440-17-7/Rubidium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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