| Effects of peripheral neuropathy on exercise capacity and quality of life in patients with chronic obstructive pulmonary diseases. | |
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MedLine Citation:
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PMID: 22662003 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Chronic obstructive pulmonary diseases (COPD) have some systemic effects including systemic inflammation, nutritional abnormalities, skeletal muscle dysfunction, and cardiovascular, skeletal and neurological disorders. Some studies have reported the presence of peripheral neuropathy (PNP) at an incidence of 28-94% in patients with COPD. Our study aimed to identify whether PNP affects exercise performance and quality of life in COPD patients. MATERIAL AND METHODS: Thirty mild-very severe patients with COPD (male/female = 29/1, mean age = 64 ±10 years) and 14 normal subjects (male/female = 11/5, mean age = 61 ±8 years) were included in the present study. All subjects underwent pulmonary function testing (PFT), cardiopulmonary exercise testing, electroneuromyography and short form 36 (SF-36). RESULTS: Peak oxygen uptake (PeakVO(2)) was lower in COPD patients (1.15 ±0.53 l/min) than healthy subjects (2.02 ±0.46 l/min) (p = 0.0001). There was no PNP in healthy subjects while 16 (53%) of the COPD patients had PNP. Forced expiratory volume in 1 s (FEV(1)) and PeakVO(2) were significantly different between patients with PNP and those without (p = 0.009, p = 0.03 respectively). Quality of life of patients with PNP was lower than that of patients without PNP (p < 0.05). CONCLUSIONS: The present study demonstrates the exercise limitation in COPD patients with PNP. Thus, presence of PNP has a poor effect on exercise capacity and quality of life in patients with COPD. Furthermore, treatment modalities for PNP can be recommended to these patients in order to improve exercise capacity and quality of life. |
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Authors:
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Gaye Ulubay; Sevinc Sarinc Ulasli; Serife Savas Bozbas; Tugce Ozdemirel; Metin Karatas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of medical science : AMS Volume: 8 ISSN: 1896-9151 ISO Abbreviation: Arch Med Sci Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-06-04 Completed Date: 2012-10-02 Revised Date: 2013-03-05 |
Medline Journal Info:
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Nlm Unique ID: 101258257 Medline TA: Arch Med Sci Country: Poland |
Other Details:
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Languages: eng Pagination: 296-302 Citation Subset: - |
Affiliation:
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Department of Pulmonary Diseases, Faculty of Medicine, Baskent University, Ankara, Turkey. |
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