| Effects of pelvic floor muscle contraction on anal canal pressure. | |
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MedLine Citation:
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PMID: 17023551 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The role of pelvic floor muscle contraction in the genesis of anal canal pressure is not clear. Recent studies have suggested that vaginal distension increases pelvic floor muscle contraction. We studied the effects of vaginal distension on anal canal pressure in 15 nullipara asymptomatic women. Anal pressure, rest, and squeeze were measured using station pull-through manometry techniques with no vaginal probe, a 10-mm vaginal probe, and a 25-mm vaginal probe in place. Rest and squeeze vaginal pressures were significantly higher when measured with the 25-mm probe compared with the 10-mm probe, suggesting that vaginal distension enhances pelvic floor contraction. In the presence of the 25-mm vaginal probe, rest and squeeze anal pressures in the proximal part of the anal canal were significantly higher compared with no vaginal probe or the 10-mm vaginal probe. On the other hand, distal anal pressures were not affected by any of the vaginal probes. Ultrasound imaging of the pelvic floor revealed that vaginal distension increased the anterior-posterior length of the puborectalis muscle. Atropine at 15 micro g/kg had no influence on the rest and squeeze anal pressures with or without vaginal distension. Our data suggest that pelvic floor contractions increase pressures in the proximal part of the anal canal, which is anatomically surrounded by the puborectalis muscle. We propose that pelvic floor contraction plays an important role in the fecal continence mechanism by increasing anal canal pressure. |
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Authors:
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Bikram S Padda; Sung-Ae Jung; Dolores Pretorius; Charles W Nager; Debbie Den-Boer; Ravinder K Mittal |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural Date: 2006-10-05 |
Journal Detail:
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Title: American journal of physiology. Gastrointestinal and liver physiology Volume: 292 ISSN: 0193-1857 ISO Abbreviation: Am. J. Physiol. Gastrointest. Liver Physiol. Publication Date: 2007 Feb |
Date Detail:
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Created Date: 2007-02-09 Completed Date: 2007-04-16 Revised Date: 2007-12-03 |
Medline Journal Info:
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Nlm Unique ID: 100901227 Medline TA: Am J Physiol Gastrointest Liver Physiol Country: United States |
Other Details:
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Languages: eng Pagination: G565-71 Citation Subset: IM |
Affiliation:
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Univ of California San Diego, La Jolla, CA 92161, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anal Canal / drug effects, physiology*, physiopathology Atropine / pharmacology Female Humans Manometry Middle Aged Muscle Contraction / drug effects, physiology* Muscle, Skeletal / physiology*, physiopathology Parasympatholytics / pharmacology Pelvic Floor / physiology*, physiopathology Pressure Vagina / drug effects, physiology, physiopathology |
| Grant Support | |
ID/Acronym/Agency:
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R01-DK-60733/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Parasympatholytics; 51-55-8/Atropine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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