| Effects of pectin on fatty acid and glucose absorption and on thickness of unstirred water layer in rat and human intestine. | |
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MedLine Citation:
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PMID: 2545425 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Effects of pectin, a soluble dietary fiber, on fatty acid and glucose absorption were studied in vivo in rats and humans by perfusing the intestine with linoleic acid and glucose solutions with and without pectin. Linoleic acid and glucose absorption decreased with increasing concentrations of pectin. The reduction in linoleic acid absorption was not caused by binding of linoleic acids by pectin or impaired micelle formation due to binding of bile acid by pectin. The unstirred water layer expanded with increasing concentrations of pectin. These results suggest that enlargement of the unstirred water layer is closely associated with the reduction of absorption of fatty acid and glucose ingested with pectin. |
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Authors:
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K Fuse; T Bamba; S Hosoda |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 34 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 1989 Jul |
Date Detail:
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Created Date: 1989-08-16 Completed Date: 1989-08-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1109-16 Citation Subset: AIM; IM |
Affiliation:
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Second Department of Internal Medicine, Shiga University of Medical Science, Ohtsu, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Animals Body Water / metabolism* Dietary Carbohydrates / metabolism* Dietary Fats / metabolism* Dietary Fiber / pharmacology* Female Glucose / pharmacokinetics Humans Intestinal Absorption* Linoleic Acid Linoleic Acids / pharmacokinetics Male Pectins / pharmacology* Potentiometry Rats Rats, Inbred Strains |
| Chemical | |
Reg. No./Substance:
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0/Dietary Carbohydrates; 0/Dietary Fats; 0/Linoleic Acids; 0/Pectins; 2197-37-7/Linoleic Acid; 50-99-7/Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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