Document Detail

Effects of paralysis with pancuronium bromide on joint mobility in premature infants.
MedLine Citation:
PMID:  7608799     Owner:  NLM     Status:  MEDLINE    
To study the effects of muscle paralysis on joint mobility, we compared eight premature infants treated with pancuronium bromide with a control group. A significant reduction was observed in hip and knee flexion, and in ankle dorsal extension, which tended to resolve in time. We conclude that muscle paralysis reduces the mobility of selected joints; spontaneous activity appears to prevent long-term contractures.
S Fanconi; S Ensner; B Knecht
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  127     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-08-11     Completed Date:  1995-08-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  134-6     Citation Subset:  AIM; IM    
Intensive Care Unit, University Children's Hospital, Zürich, Switzerland.
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MeSH Terms
Ankle / physiopathology
Hip / physiopathology
Infant, Newborn
Infant, Premature*
Knee Joint / physiopathology
Muscle Contraction / drug effects
Muscles / physiopathology*
Pancuronium / adverse effects*,  pharmacology*,  therapeutic use
Paralysis / etiology*,  physiopathology*
Prospective Studies
Respiration, Artificial
Respiratory Distress Syndrome, Newborn / drug therapy*,  therapy
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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