| Effects of oral contraceptives on lipoprotein triglyceride and cholesterol: relationships to estrogen and progestin potency. | |
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MedLine Citation:
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PMID: 7065054 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hormone formulation and estrogen/progestin potency were evaluated in relation to triglyceride and cholesterol concentrations in total plasma and lipoprotein fractions and in relation to lipid composition among a random sample of female telephone company personnel. Triglyceride concentrations in whole plasma, very low-density lipoprotein, and high-density lipoprotein (HDL) were elevated in response to increasing estrogen potency as were triglyceride concentrations in low-density lipoprotein (LDL). LDL cholesterol rose with increasing estrogen potency in contraceptive users but was slightly lower in postmenopausal estrogen-treated women. Plasma HDL cholesterol varied according to estrogen and progestin levels. The LDL cholesterol/triglyceride ratio was reduced for all combination oral contraceptives examined. Sequential oral contraceptives of postmenopausal estrogens did not significantly alter the cholesterol/triglyceride ratio in any lipoprotein fraction. Potential arteriosclerotic risk from sex hormone use may vary among oral contraceptive formulations. |
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Authors:
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R H Knopp; C E Walden; P W Wahl; J J Hoover |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 142 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1982 Mar |
Date Detail:
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Created Date: 1982-05-27 Completed Date: 1982-05-27 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 725-31 Citation Subset: AIM; IM; J |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cholesterol / blood Contraceptives, Oral / pharmacology* Contraceptives, Oral, Hormonal / pharmacology* Estrogens / pharmacology* Female Humans Lipids / blood* Lipoproteins / blood Middle Aged Progestins / pharmacology* Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Contraceptives, Oral; 0/Contraceptives, Oral, Hormonal; 0/Estrogens; 0/Lipids; 0/Lipoproteins; 0/Progestins; 0/Triglycerides; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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