Document Detail


Effects of opiate receptor ligands on DNA synthesis in tracheal epitheliocytes and smooth muscle cells of newborn albino rats.
MedLine Citation:
PMID:  11391405     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The dermorphin analogue A10 injected to newborn rats from the 2nd to 6th day of life increased the index of labeled nuclei in epitheliocytes and smooth muscle cells and labeling intensity in smooth muscle cells. Dynorphin A(1-13)increased the index of labeled nuclei and labeling intensity in epitheliocytes and labeling intensity in smooth muscle cells. Dalargin increased the labeling intensity in epitheliocytes, but had effect on DNA synthesis in muscle cells.
Authors:
O A Lebed'ko; S S Timoshin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bulletin of experimental biology and medicine     Volume:  131     ISSN:  0007-4888     ISO Abbreviation:  Bull. Exp. Biol. Med.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-06-06     Completed Date:  2001-12-28     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0372557     Medline TA:  Bull Exp Biol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  169-71     Citation Subset:  IM    
Affiliation:
Institute of Maternity and Child Welfare, Khabarovsk Branch, Far-Eastern State Medical University, Khabarovsk, Russia.
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MeSH Terms
Descriptor/Qualifier:
Analgesics / pharmacology
Analgesics, Opioid / pharmacology
Animals
Animals, Newborn
Antioxidants / metabolism
Cell Division / drug effects
DNA / biosynthesis*
Enkephalin, Leucine-2-Alanine / analogs & derivatives*,  pharmacology
Epithelial Cells / drug effects*,  metabolism
Ligands
Lipid Metabolism
Lung / metabolism
Muscle, Smooth / cytology*,  drug effects,  metabolism
Oligopeptides / chemistry,  pharmacology*
Opioid Peptides
Rats
Receptors, Opioid / agonists*,  metabolism
Trachea / cytology*,  drug effects
Chemical
Reg. No./Substance:
0/Analgesics; 0/Analgesics, Opioid; 0/Antioxidants; 0/Ligands; 0/Oligopeptides; 0/Opioid Peptides; 0/Receptors, Opioid; 63631-40-3/Enkephalin, Leucine-2-Alanine; 77614-16-5/dermorphin; 81733-79-1/enkephalin-Leu, Ala(2)-Arg(6)-; 9007-49-2/DNA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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