Document Detail

Effects of open vs. closed system endotracheal suctioning on cerebral blood flow velocities in mechanically ventilated extremely low birth weight infants.
MedLine Citation:
PMID:  16238539     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Endotracheal (ET) suctioning causes cardiovascular side effects and may impair cerebral hemodynamics. Subjectively, these effects are worse if patients are disconnected from the ventilator (open system suctioning, OSS) than if they remain connected to the ventilator during suctioning (closed system suctioning, CSS). It is uncertain whether the response to ET suctioning is similar in conventionally (CV) and high frequency (HF) ventilated patients. OBJECTIVES: To investigate if the mode of suctioning or of mechanical ventilation influences cerebral blood flow velocities (CBFVs) in extremely low birth weight (ELBW) infants. METHODS: Transcranial Doppler sonography in the middle cerebral artery during OSS and CSS in CV and HF ventilated ELBW infants. RESULTS: Forty-one measurements were performed in 19 infants within the first two weeks of life. Mean CBFVs decreased during suctioning from baseline 18.8 to 14.3 cm/s (-24%), increased thereafter to 24.7 cm/s (73%) and then returned to baseline (20.8 cm/s). Changes in CBFV were less pronounced in infants with higher baseline CBFVs. Heart rate decreased during ET suctioning and thereafter returned to baseline values. The alterations in CBFV and heart rate were both independent of the mode of ventilation or suctioning. CONCLUSIONS: The mode of suctioning or ventilation does not influence CBFVs in ELBW infants.
Hannes Rieger; Stefan Kuhle; Osman S Ipsiroglu; Harald Heinzl; Christian N Popow
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  33     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2005  
Date Detail:
Created Date:  2005-10-21     Completed Date:  2005-12-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  435-41     Citation Subset:  IM    
Department of Pediatrics, Medical University of Vienna, Austria.
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MeSH Terms
Blood Flow Velocity
High-Frequency Ventilation*
Infant, Newborn
Infant, Very Low Birth Weight*
Intubation, Intratracheal
Middle Cerebral Artery / physiology*,  ultrasonography
Pulsatile Flow
Respiratory Distress Syndrome, Adult / physiopathology*
Telencephalon / blood supply*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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