Document Detail


Effects of ocular decongestants.
MedLine Citation:
PMID:  7378008     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Eight widely used commercially available ocular decongestants were compared on the basis of vasoconstrictive effectiveness. The ability of these preparations to counteract histamine-induced erythema and to block its recurrence when rechallenged after one hour was evaluated in six human subjects in seven sessions. All vasoconstrictors tested were effective. No preparation was statistically different from 0.02% naphazoline hydrochloride in vasoconstrictive effect. In fact, this intermediate concentration of naphazoline (0.02%) was found to be significantly better that the other nonprescription decongestant preparations tested as a group and not significantly different from a group of higher concentrations of naphazoline.
Authors:
M B Abelson; G K Yamamoto; M R Allansmith
Related Documents :
3711548 - Discrimination between urticaria-prone and other allergic patients by intradermal skin ...
18797058 - Comparative efficacy of levocetirizine, desloratidine and fexofenadine by histamine whe...
2461108 - Basophil histamine release in children with adverse reactions to cow milk. comparison w...
2600328 - The hymenoptera venom study. ii: skin test results and safety of venom skin testing.
19005818 - The bait-lamina test : general aspects, applications and perspectives.
12619188 - Perioperative stroke in the brain and spinal cord following an induced hypotension.
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of ophthalmology     Volume:  98     ISSN:  0003-9950     ISO Abbreviation:  Arch. Ophthalmol.     Publication Date:  1980 May 
Date Detail:
Created Date:  1980-07-12     Completed Date:  1980-07-12     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7706534     Medline TA:  Arch Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  856-8     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Antipyrine / pharmacology
Cornea / blood supply*
Double-Blind Method
Humans
Imidazoles / pharmacology
Naphazoline / pharmacology
Nonprescription Drugs
Phenylephrine / pharmacology
Tetrahydronaphthalenes / pharmacology
Vasoconstrictor Agents / administration & dosage,  pharmacology*
Vasodilation / drug effects*
Chemical
Reg. No./Substance:
0/Imidazoles; 0/Nonprescription Drugs; 0/Tetrahydronaphthalenes; 0/Vasoconstrictor Agents; 59-42-7/Phenylephrine; 60-80-0/Antipyrine; 835-31-4/Naphazoline; 84-22-0/tetrahydrozoline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Cocaine toxicity during dacryocystorhinostomy.
Next Document:  Baring of the circumlinear vessel. An early sign of optic nerve damage.