Document Detail


Effects of normobaric and hypobaric hypoxia on ventilation and arterial blood gases in ducks.
MedLine Citation:
PMID:  2218098     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We measured ventilation (V1) and arterial blood gases in awake Pekin ducks exposed to normoxia at sea level, normobaric hypoxia achieved by lowering FIO2 at normal barometric pressure (NORMO), and hypobaric hypoxia achieved with a low pressure chamber and 21% O2 (HYPO). Average normoxic values were: V1 = 0.46 L . (kg.min)-1, PaO2 = 99.7 Torr, PaCO2 = 30.1 Torr. At PIO2 = 90 Torr, NORMO and HYPO measurements were not significantly different (P greater than 0.05). At PO2 = 46 Torr, NORMO V1 was less than HYPO V1 but blood gases were not significantly different: VI = 1.00 vs 1.45 L . (kg.min)-1; PaO2 = 31.3 vs 33.0 Torr; PaCO2 = 11.5 vs 10.6 Torr. Although both tidal volume (VT) and respiratory frequency (fR) were greater in HYPO, similar blood gases with NORMO and HYPO suggest similar parabronchial ventilation. The results suggest increased physiologic dead space, caused by reduced efficacy of aerodynamic valving, with reduced gas density in hypobaria.
Authors:
H Shams; F L Powell; S C Hempleman
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Respiration physiology     Volume:  80     ISSN:  0034-5687     ISO Abbreviation:  Respir Physiol     Publication Date:    1990 May-Jun
Date Detail:
Created Date:  1990-10-31     Completed Date:  1990-10-31     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0047142     Medline TA:  Respir Physiol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  163-70     Citation Subset:  IM    
Affiliation:
Department of Medicine, University of California, San Diego, La Jolla.
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MeSH Terms
Descriptor/Qualifier:
Air Pressure*
Animals
Anoxia / blood*
Blood Gas Analysis
Ducks / physiology*
Pulmonary Circulation / physiology
Ventilation-Perfusion Ratio / physiology*
Grant Support
ID/Acronym/Agency:
HL 173301/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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