Document Detail


Effects of neuromuscular blockade on fetal heart rate variability: a power spectrum analysis.
MedLine Citation:
PMID:  7559248     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Spectral analysis of fetal heart rate variability allows quantitative determination of the main components that affect this variability. The physiological significance of these components is unclear; however, movements appear to contribute to variability. We studied six fetuses in which immobility required for in utero magnetic resonance or invasive fetal procedures was achieved by fetal intravascular injection of curare between 32 and 36 amenorrhea weeks. For each fetus, we compared spectral density parameters of heart rate variability. After curare administration, mean spectrum power was halved. We did not observe a larger significant decrease in any (very low, low, or high) frequency band. The other parameters of spectral analysis of variability were unaltered. Fetal movements accounted for a significant proportion of human fetal heart rate variability but did not constitute a unique frequency component.
Authors:
O Sibony; J P Fouillot; D Luton; J F Oury; P Blot
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of applied physiology (Bethesda, Md. : 1985)     Volume:  79     ISSN:  8750-7587     ISO Abbreviation:  J. Appl. Physiol.     Publication Date:  1995 Jul 
Date Detail:
Created Date:  1995-11-14     Completed Date:  1995-11-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8502536     Medline TA:  J Appl Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  63-5     Citation Subset:  IM    
Affiliation:
Département de Périnatologie, Hôpital Robert Debré, Paris, France.
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MeSH Terms
Descriptor/Qualifier:
Curare / pharmacology*
Female
Heart Rate, Fetal / drug effects*
Humans
Neuromuscular Blocking Agents / pharmacology*
Pregnancy
Chemical
Reg. No./Substance:
0/Neuromuscular Blocking Agents; 8063-06-7/Curare

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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