Document Detail

Effects of nebulized fenoterol, associated with ipratropium or steroids, on the heart rate of infants under one year of age with acute wheezing.
MedLine Citation:
PMID:  2954024     Owner:  NLM     Status:  MEDLINE    
The main objective of this study was to evaluate the effect of fenoterol alone or associated with ipratropium bromide or steroid on the heart rate in young children. Ninety-four infants less than 1 year of age were randomly allocated to receive nebulized fenoterol alone, fenoterol plus ipratropium bromide, fenoterol plus corticosteroids, or normal saline solution. An increase in heart rate was observed in all four groups. The increases were statistically significant (P less than 0.001) in all three treatment groups, and no difference between them was observed (F = 0.65, NS). However, the heart rate remained within clinically acceptance limits. We conclude that nebulized fenoterol alone or combined with ipratropium or steroids can be safely used in the treatment of wheezy infants.
J Mallol; R Muñoz; H Puppo; V Ulloa; O Toro; G Girardi; L Barrueto
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Pediatric pulmonology     Volume:  3     ISSN:  8755-6863     ISO Abbreviation:  Pediatr. Pulmonol.     Publication Date:    1987 Mar-Apr
Date Detail:
Created Date:  1987-06-30     Completed Date:  1987-06-30     Revised Date:  2006-03-28    
Medline Journal Info:
Nlm Unique ID:  8510590     Medline TA:  Pediatr Pulmonol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  83-5     Citation Subset:  IM    
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MeSH Terms
Acute Disease
Adrenal Cortex Hormones / pharmacology*
Atropine Derivatives / pharmacology*
Drug Therapy, Combination
Fenoterol / pharmacology*
Heart Rate / drug effects*
Ipratropium / pharmacology*
Respiratory Sounds / physiopathology*
Reg. No./Substance:
0/Adrenal Cortex Hormones; 0/Aerosols; 0/Atropine Derivatives; 13392-18-2/Fenoterol; 60205-81-4/Ipratropium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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