Document Detail

Effects of nasopharyngeal cocaine or pharyngeal benzocaine on esophageal motility.
MedLine Citation:
PMID:  3812417     Owner:  NLM     Status:  MEDLINE    
The esophageal effect of topical anesthetics applied to the nasopharynx was evaluated. Eight healthy volunteers underwent an esophageal motility study after each of the following: no anesthesia, 5% cocaine solution applied to the nasopharynx, and 20% benzocaine spray applied to the pharynx. Upper esophageal sphincter relaxation was prolonged after use of the 5% cocaine solution. No other significant effects on esophageal motility or pressures were noted.
J F Hacker; E L Cattau
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of gastroenterology     Volume:  82     ISSN:  0002-9270     ISO Abbreviation:  Am. J. Gastroenterol.     Publication Date:  1987 Feb 
Date Detail:
Created Date:  1987-03-10     Completed Date:  1987-03-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0421030     Medline TA:  Am J Gastroenterol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  127-9     Citation Subset:  IM    
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MeSH Terms
Administration, Intranasal
Anesthesia, Local*
Benzocaine / administration & dosage,  pharmacology*
Cocaine / administration & dosage,  pharmacology*
Esophagogastric Junction / drug effects
Esophagus / drug effects*
Gastrointestinal Motility / drug effects*
Reg. No./Substance:
50-36-2/Cocaine; 94-09-7/Benzocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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