| Effects of nasal continuous positive airway pressure (NCPAP) on breathing pattern in spontaneously breathing premature newborn infants. | |
| | |
MedLine Citation:
|
PMID: 11810123 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: The aim of the study was to assess the influence of nasal continuous positive airway pressure (NCPAP) on breathing pattern in preterm newborns. DESIGN: Prospective study. SETTING: Neonatal intensive care unit. PATIENTS: Ten premature newborn infants on NCPAP (gestational age range from 27 to 32 weeks, mean birth weight 1300+/-460 g) admitted in our neonatal intensive care unit (NICU) for respiratory distress syndrome. METHODS: Breathing patterns and changes in lung volumes level were obtained using respiratory inductive plethysmography (RIP), at random CPAP levels (0, 2, 4, 6 and 8 cmH2O). Raw data were analysed for end-expiratory lung volume level (EELV-level), tidal volume (Vt), respiratory rate, phase angle and labour breathing index (LBI). RESULTS: CPAP increased EELV-level by 2.1+/-0.3xVt from 0 to 8 cmH2O ( p<0.01). Vt increased by 43% from CPAP of 0 cmH2O to CPAP of 8 cmH2O ( p<0.01). We also found that CPAP lowered the phase angle (from 76+/-21 degrees at CPAP of 0 cmH2O to 30+/-15 degrees at CPAP of 8 cmH2O; p<0.01 ) and LBI (from 1.7+/-0.8 at CPAP of 0 cmH2O to 1.2+/-0.3 at CPAP of 8 cmH2O; p<0.05). CONCLUSION: NCPAP improves the breathing strategy of premature infants with respiratory failure, as reflected by improved thoraco-abdominal synchrony, increased Vt and reduction of the LBI. This effect is associated with an increase in EELV-level with CPAP level. However, further investigations are necessary to establish the best CPAP level that ensures both safety and efficiency. |
| | |
Authors:
|
A Elgellab; Y Riou; A Abbazine; P Truffert; R Matran; P Lequien; L Storme |
Related Documents
:
|
22016793 - Molecular identification of bacteria in tracheal aspirate fluid from mechanically venti... 22189523 - Impact of 4.0% chlorhexidine cord cleansing on the bacteriological profile of the newbo... 8791193 - Effects of twinning on dystocia, calf survival, calf growth, carcass traits, and cow pr... |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Randomized Controlled Trial Date: 2001-10-31 |
Journal Detail:
|
Title: Intensive care medicine Volume: 27 ISSN: 0342-4642 ISO Abbreviation: Intensive Care Med Publication Date: 2001 Nov |
Date Detail:
|
Created Date: 2002-01-25 Completed Date: 2002-03-28 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7704851 Medline TA: Intensive Care Med Country: United States |
Other Details:
|
Languages: eng Pagination: 1782-7 Citation Subset: IM |
Affiliation:
|
Department of Neonatology, Centre Hospitalier et Universitaire, 59037, Lille cédex, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Analysis of Variance Humans Infant, Newborn Infant, Premature Infant, Premature, Diseases / therapy* Intensive Care Units, Neonatal Lung Diseases / therapy* Plethysmography Positive-Pressure Respiration / methods* Prospective Studies Respiratory Mechanics Treatment Outcome |
| Comments/Corrections | |
Comment In:
|
Intensive Care Med. 2001 Nov;27(11):1689-91
[PMID:
11810110
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Prognostic factors in unintentional mild carbon monoxide poisoning.
Next Document: The influence of endotracheal tube leak on the assessment of respiratory function in ventilated chil...