Document Detail


Effects of multiple injections of HCG on testis blood flow.
MedLine Citation:
PMID:  1621319     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In attempting to determine whether or not multiple injections of human chorionic gonadotropin (hCG) augment testis blood flow, adult male rats were injected with three doses of 10 IU of hCG every other day and testis blood flow was determined on day 5, the day of the final injection. Testis blood flow (mL/100 g testis tissue/min +/- SEM) as measured by the 133Xe washout method increased from 10.8 +/- 1.3 to 20.4 +/- 4.5 (p less than 0.05) after the three doses of hCG. These observations suggest that multiple injections of hCG appear to have the same effect as a single dose of hCG in increasing testis blood flow. This supports the hypothesis that hCG should be administered to all patients undergoing orchiopexy in the hope that the increased perfusion of the gonad will make it less susceptible to ischemia during the surgical procedure.
Authors:
B Geesaman; J Villanueva-Meyer; D Bluestein; L Miller; I Mena; J Rajfer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Urology     Volume:  40     ISSN:  0090-4295     ISO Abbreviation:  Urology     Publication Date:  1992 Jul 
Date Detail:
Created Date:  1992-08-06     Completed Date:  1992-08-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  81-3     Citation Subset:  IM    
Affiliation:
Department of Surgery, UCLA School of Medicine, Torrance.
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MeSH Terms
Descriptor/Qualifier:
Animals
Chorionic Gonadotropin / administration & dosage,  pharmacology*
Humans
Male
Rats
Rats, Inbred Strains
Regional Blood Flow / drug effects
Stimulation, Chemical
Testis / blood supply*,  radionuclide imaging
Xenon Radioisotopes / diagnostic use
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Xenon Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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