Document Detail

Effects of monensin and amicloral on rumen fermentation.
MedLine Citation:
PMID:  7410269     Owner:  NLM     Status:  MEDLINE    
Fermentative adjustments produced by monensin and amicloral and by combinations of monensin plus amicloral were investigated in vitro. Monensin increased (P < .05) production of propionate, usually decreased production of acetate and butyrate and partially reduced methanogenesis, but no accumulation of gaseous hydrogen was observed. Amicloral not only increased production of propionate (P < .05), but also usually increased butyrate production, decreased (P < .05) acetate production and almost completely inhibited (P < .05) methanogenesis, and substantial quantities (P < .05) of hydrogen accumulated in the gas phase. Both chemical agents were effective (P < .05) in decreasing utilization of an exogenous amino acid load. Monensin plus amicloral produced fermentative adjustments comparable to those predicted from cultures medicated with monensin or amicloral alone; thus, effects mediated by the combined agents were additive and no consistent positive or negative synergestic activities were noted. Characteristic adjustments in rumen fermentation caused by monensin, by amicloral and by additivity of these adjustments are reflections of the two chemical agents manipulating ruminal reactions by different mechanisms.
W Chalupa; W Corbett; J R Brethour
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of animal science     Volume:  51     ISSN:  0021-8812     ISO Abbreviation:  J. Anim. Sci.     Publication Date:  1980 Jul 
Date Detail:
Created Date:  1980-11-24     Completed Date:  1980-11-24     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  8003002     Medline TA:  J Anim Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  170-9     Citation Subset:  IM    
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MeSH Terms
Cattle / metabolism
Fermentation / drug effects*
Furans / pharmacology*
Monensin / pharmacology*
Polysaccharides / pharmacology*
Rumen / drug effects
Reg. No./Substance:
0/Furans; 0/Polysaccharides; 17090-79-8/Monensin; 34398-83-9/amicloral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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