| Effects of mixed micellar lipids on carotenoid uptake by human intestinal caco-2 cells. | |
| | |
MedLine Citation:
|
PMID: 22738952 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
We reported previously that lysophosphatidylcholine remarkably enhanced β-carotene uptake from bile acid-mixed micelles by human intestinal Caco-2 cells. In the present study, we evaluated how mixed micelle components other than phospholipids, viz., fatty acids, monoolein, and cholesterol, affect carotenoid uptake by Caco-2 cells. Each component influenced the β-carotene uptake in a different way depending on micellar composition. Oleic acid at 200 µM significantly enhanced uptake in the absence of lysophosphatidylcholine. Cholesterol at 40 µM significantly reduced uptake in the presence of lysophosphatidylcholine, while no reduction was found in the presence of 200 µM oleic acid. Facilitated diffusion was suggested partly to mediate uptake in mixed micelles, except for mixed micelles containing 200 µM oleic acid. Uptake mediated by facilitated diffusion was approximately 20% of total uptake. Mixed micellar lipids have the potential to modify intestinal uptake. |
| | |
Authors:
|
Eiichi Kotake-Nara; Akihiko Nagao |
Publication Detail:
|
Type: Journal Article Date: 2012-05-07 |
Journal Detail:
|
Title: Bioscience, biotechnology, and biochemistry Volume: 76 ISSN: 1347-6947 ISO Abbreviation: Biosci. Biotechnol. Biochem. Publication Date: 2012 May |
Date Detail:
|
Created Date: 2012-06-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9205717 Medline TA: Biosci Biotechnol Biochem Country: Japan |
Other Details:
|
Languages: eng Pagination: 875-82 Citation Subset: IM |
Affiliation:
|
National Food Research Institute, National Agriculture and Food Research Organization. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Adsorption mechanism for xanthene dyes to cellulose granules.
Next Document: Functional Divergence of MYB-Related Genes, <i>WEREWOLF</i> and <i>AtMYB23</i> in <i>Arabidopsis</i>...