| Effects of a mineral antioxidant complex on clinical safety, body water, lactate response, and aerobic performance in response to exhaustive exercise. | |
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MedLine Citation:
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PMID: 20975106 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: This investigation examined the safety and efficacy of a silica-based mineral antioxidant complex (MAC) that has been suggested to influence body water and buffer lactate. METHODS: In a double-blind, randomized crossover design, male participants completed testing for 3 conditions: water only (baseline), rice flour (placebo), and MAC supplementation. Participants visited the laboratory on 5 occasions: familiarization, baseline, Testing Day 1, washout, and Testing Day 2. Baseline and Testing Days 1 and 2 consisted of fasting blood, pre- to postexercise body-water assessment and determination of VO2peak on a cycle ergometer. The supplementation protocols were separated by 1 wk and balanced to minimize an order effect. RESULTS: No differences between conditions were found for heart rate, blood pressure, or serum-safety markers (p>.05). Before exercise there were no differences between conditions for total body water (TBW), intracellular water (ICW), or extracellular water (ECW). No significant interactive effects for supplementation and exercise were found for TBW, ICW, or ECW (p>.05). A time effect for TBW (p<.01) and ICW (p<.001) was present. Within-group changes in TBW occurred in the MAC condition, and within-group changes for ICW occurred in the MAC and placebo conditions. Ratings of perceived exertion and blood lactate increased (p<.05) with exercise. No significant effects were found for performance variables. CONCLUSIONS: MAC supplementation had no impact on aerobic exercise performance and lactate response. Increases in TBW and ICW occurred after MAC consumption, but these changes appeared to have minimal physiological impact. |
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Authors:
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Vincent J Dalbo; Michael D Roberts; Scott E Hassell; Jordan R Moon; Chad M Kerksick |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International journal of sport nutrition and exercise metabolism Volume: 20 ISSN: 1526-484X ISO Abbreviation: Int J Sport Nutr Exerc Metab Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-26 Completed Date: 2010-11-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100939812 Medline TA: Int J Sport Nutr Exerc Metab Country: United States |
Other Details:
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Languages: eng Pagination: 381-92 Citation Subset: IM |
Affiliation:
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School of Medicine and Applied Sciences, Central Queensland University, Rockhampton, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antioxidants
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administration & dosage,
adverse effects,
pharmacology* Bicycling / physiology Body Water / metabolism* Consumer Product Safety Cross-Over Studies Dietary Supplements Double-Blind Method Electric Impedance Humans Lactates / metabolism* Male Minerals / administration & dosage, adverse effects, pharmacology* Physical Exertion / drug effects*, physiology Silicon Dioxide / administration & dosage, adverse effects, pharmacology Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Lactates; 0/Minerals; 7631-86-9/Silicon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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