Document Detail

Effects of maternal smoking on fetal organs.
MedLine Citation:
PMID:  23240449     Owner:  NLM     Status:  In-Process    
BACKGROUND: Unfavorable effects of in-utero smoke exposure have been shown in several studies.
OBJECTIVES: In this experimental study, the authors aimed at showing detrimental effects of cigarette smoke on fetal tissues by assessing apoptosis that is detected by performing TUNEL staining.
MATERIAL AND METHODS: Designed groups were smoke exposed rats before and during pregnancy and control groups. Rat offsprings were sacrificed when they were 12 days old.
RESULTS: Lung, kidney, adrenal and gonad tissues were harvested for histopathologic analysis and assessed by TUNEL (Terminal dUTP Nick End Labeling) staining.
CONCLUSIONS: Smoke exposure caused increased apoptotic activity in lung parenchyma of study groups.
Abdulbaki Karaoglu; Turan Tunc; Gokhan Aydemir; Onder Ongoru; Secil Aydinoz; Bulent Uysal; Galip Erdem; Ahmet Guven; Emin Oztas; S Umit Sarici
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Advances in clinical and experimental medicine : official organ Wroclaw Medical University     Volume:  21     ISSN:  1899-5276     ISO Abbreviation:  Adv Clin Exp Med     Publication Date:    2012 Jul-Aug
Date Detail:
Created Date:  2012-12-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101138582     Medline TA:  Adv Clin Exp Med     Country:  Poland    
Other Details:
Languages:  eng     Pagination:  441-6     Citation Subset:  IM    
Gulhane Military Medical Faculty, Department of Pediatrics, Ankara, Turkey.
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