Document Detail


Effects of maternal geophagia on infant and juvenile rats.
MedLine Citation:
PMID:  6631996     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Clay eating, a form of geophagia, is often observed in the human population, particularly during pregnancy. The intent of this study was to determine the effects of maternal geophagia on developmental and behavioral characteristics of the offspring. Twelve Sprague-Dawley female rats and their 88 progeny were divided into three groups: control, 20 percent clay, and 35 percent clay. The experimental diets were fed to adult rats during the period of gestation and for 14 days following parturition. Righting reflex, homing response, and activity level tests were administered and hemoglobin concentrations and red blood cell counts were determined. Data suggest that the higher level of maternal clay ingestion during the perinatal period decreased growth and development of motor skills in the infant pups. Homing skills, however, were enhanced.
Authors:
A A Edwards; C B Mathura; C H Edwards
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of the National Medical Association     Volume:  75     ISSN:  0027-9684     ISO Abbreviation:  J Natl Med Assoc     Publication Date:  1983 Sep 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  7503090     Medline TA:  J Natl Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  895-902     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aluminum Silicates / adverse effects
Animals
Female
Humans
Male
Maternal-Fetal Exchange
Motor Skills
Pica*
Pregnancy
Pregnancy Complications*
Prenatal Exposure Delayed Effects*
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
0/Aluminum Silicates; 1302-87-0/clay
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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