Document Detail


Effects of low dose tryptophan depletion on emotional processing in dieters.
MedLine Citation:
PMID:  22365802     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Biased processing of ED-relevant stimuli (eg Fairburn, Shafran, & Cooper, 1999) and 5-HT function (Kaye, Fudge, & Paulus, 2009) are implicated in vulnerability to and the maintenance of eating disorders (EDs), but it is not known if these findings are connected: Could manipulating 5-HT function affect the processing of ED-relevant stimuli? To address this question we assessed emotional processing in female dieters (T+n=12, T-n=14) following acute low dose tryptophan depletion. ATD increased interference in the masked condition of the emotional Stroop to all negative emotional stimuli, in the absence of any other differences in emotional processing. These results suggest that ATD affects the processing of some negative (including ED-relevant) stimuli, and that reduced 5-HT function may be involved in some aspects of psychological vulnerability to EDs.
Authors:
A Pringle; M J Cooper; M Browning; C J Harmer
Publication Detail:
Type:  Journal Article     Date:  2012-01-08
Journal Detail:
Title:  Eating behaviors     Volume:  13     ISSN:  1873-7358     ISO Abbreviation:  Eat Behav     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-02-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101090048     Medline TA:  Eat Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  154-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Psychiatry, University of Oxford, United Kingdom.
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