Document Detail

Effects of a low-dose amino acid supplement on adaptations to cycling training in untrained individuals.
MedLine Citation:
PMID:  9407256     Owner:  NLM     Status:  MEDLINE    
The purpose of this study was to determine if amino acid supplementation influences blood and muscle lactate response to exercise and the time course of the metabolic adaptations to training. Two groups of untrained males (n = 7 each) were given (double-blind) a daily supplement (2.9 containing a mixture of leucine, isoleucine, valine, glutamine, and carnitine (EXP) or 3 of lactose (CON). Following 7 days of supplementation there was no significant change in VO2peak, time to exhaustion (TTX) at 120% VO2peak, or muscle and blood lactate in either EXP or CON. Subjects then initiated 6 weeks of combined aerobic and anaerobic training on a Monark cycle ergometer. It was found that amino acid supplementation had no effect on either blood or muscle lactate accumulation during exercise, while supplementation resulted in a faster adaptation in buffer capacity. Performance during intense exercise was not improved with amino acid supplementation.
M D Vukovich; R L Sharp; L D Kesl; D L Schaulis; D S King
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  International journal of sport nutrition     Volume:  7     ISSN:  1050-1606     ISO Abbreviation:  Int J Sport Nutr     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-01-20     Completed Date:  1998-01-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9307702     Medline TA:  Int J Sport Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  298-309     Citation Subset:  IM; S    
Human Performance Laboratory, Wichita State University, KS 67226, USA.
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MeSH Terms
Adaptation, Physiological*
Amino Acids / administration & dosage*
Exercise / physiology*
Hydrogen-Ion Concentration
Lactic Acid / blood,  metabolism
Lactose / administration & dosage
Muscle, Skeletal / metabolism
Oxygen Consumption
Physical Endurance*
Time Factors
Reg. No./Substance:
0/Amino Acids; 50-21-5/Lactic Acid; 63-42-3/Lactose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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