Document Detail

Effects of lotrafilcon A and omafilcon A bandage contact lenses on visual outcomes after photorefractive keratectomy.
MedLine Citation:
PMID:  18655978     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To evaluate postoperative healing between bandage contact lenses with high and low oxygen permeability in patients having photorefractive keratectomy (PRK). SETTING: Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, DC, USA. METHODS: This retrospective study compared patients receiving a high-oxygen-transmission bandage contact lens (Focus Night & Day [N&D], Ciba Vision; n = 92) and those receiving a low-oxygen-transmission lens (Proclear, Cooper Vision; n = 114) after PRK. Visual outcomes, safety, and efficacy were assessed postoperatively at 1, 4, and 7 days and 1, 3, 6, and 12 months. RESULTS: Overall pain scores were higher in the Proclear group at 1 day (P = .000) and 4 days (P = .027). The N&D group had an increase in corneal infiltrates at 4 days (P = .025) and 1 week (P = .017). At 1 month, 40.4% of patients in the Proclear group and 18.6% in the N&D group had a 1 or more line decrease in best spectacle-corrected visual acuity (BSCVA) (P = .002). Although there was a trend toward a higher haze rate in the Proclear group, it was not statistically significant (P = .064). There was no statistically significant difference in uncorrected visual acuity, goal of emmetropia, contrast sensitivity, or reepithelialization. CONCLUSIONS: The N&D lens produced less pain and better postoperative results in terms of haze and BSCVA at 1 month. However, it led to a higher incidence of corneal infiltrates. There was no difference between the lenses in the end result at 12 months.
Jayson D Edwards; Kraig S Bower; Denise A Sediq; Jenna M Burka; Richard D Stutzman; Cameron R Vanroekel; Chrystyna P Kuzmowych; Jennifer B Eaddy
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of cataract and refractive surgery     Volume:  34     ISSN:  0886-3350     ISO Abbreviation:  J Cataract Refract Surg     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-28     Completed Date:  2008-09-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8604171     Medline TA:  J Cataract Refract Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1288-94     Citation Subset:  IM    
Center for Refractive Surgery, Walter Reed Army Medical Center, Washington, DC 20307-5001, USA. <>
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MeSH Terms
Contact Lenses, Hydrophilic*
Lasers, Excimer / therapeutic use
Middle Aged
Myopia / physiopathology,  surgery*
Occlusive Dressings*
Oxygen / metabolism
Photorefractive Keratectomy*
Retrospective Studies
Treatment Outcome
Visual Acuity / physiology*
Wound Healing / physiology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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