Document Detail

Effects of long-term exercise rehabilitation on claudication distances in patients with peripheral arterial disease: a randomized controlled trial.
MedLine Citation:
PMID:  12042688     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To determine if improvements in physical function and peripheral circulation after 6 months of exercise rehabilitation could be sustained over a subsequent 12-month maintenance exercise program in older patients with intermittent claudication. METHODS: Seventeen patients randomized to exercise rehabilitation and 14 patients randomized to usual care control completed this 18-month study. Patients exercised three times per week during the first 6 months of a progressive exercise program, followed by two times per week during the final 12 months of a maintenance program. Patients were studied at baseline, 6 months, and 18 months during the study. RESULTS: Eighteen months of exercise rehabilitation increased the initial claudication distance by 373 meters (189%) (P <.001), the absolute claudication distance by 358 meters (80%) (P <.001), walking economy by 11% (P <.001), 6-minute walk distance by 10% (P <.001), daily physical activity by 31%, and maximal calf blood flow by 18% (P <.001). These changes were similar to those found after 6 months of exercise rehabilitation (P = NS), and were significantly greater than the changes in the control group throughout the study (P <.05). CONCLUSION: Improvements in claudication distances, walking economy, 6-minute walk distance, physical activity level, and peripheral circulation after 6 months of exercise rehabilitation are sustained for an additional 12 months in older patients with intermittent claudication using a less frequent exercise maintenance program.
Andrew W Gardner; Leslie I Katzel; John D Sorkin; Andrew P Goldberg
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of cardiopulmonary rehabilitation     Volume:  22     ISSN:  0883-9212     ISO Abbreviation:  J Cardiopulm Rehabil     Publication Date:    2002 May-Jun
Date Detail:
Created Date:  2002-06-03     Completed Date:  2002-08-22     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8511296     Medline TA:  J Cardiopulm Rehabil     Country:  United States    
Other Details:
Languages:  eng     Pagination:  192-8     Citation Subset:  IM    
Claude D. Pepper Older Americans Independence Center, Department of Medicine, Division of Gerontology, University of Maryland, Baltimore, USA.
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MeSH Terms
Exercise Therapy* / methods
Intermittent Claudication / rehabilitation*
Leg / blood supply
Regional Blood Flow
Time Factors
Walking / physiology*
Grant Support
Comment In:
J Cardiopulm Rehabil. 2002 May-Jun;22(3):199-200   [PMID:  12042689 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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