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THE EFFECTS OF LIPOPROTEIN (A) AND HOMOCYSTEINE ON PROGNOSIS AND RISK FACTORS IN ACUTE ISCHEMIC STROKE.
MedLine Citation:
PMID:  23384529     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Abstract The role of atherosclerosis in ischemic stroke has been intensively investigated in recent years, and homocysteine and Lp(a) were found to have roles during the process. This study aims to investigate the relationship between acute ischemic stroke and Lp(a) and Hcy levels and to determine the prognosis and functional disability. Forty-one patients with acute ischemic stroke and 33 controls were included in the study. Lp(a) and Hcy levels were examined in both groups. The modified Rankin scale (MRS) scores at discharge and in the first and third months were determined to establish the functional disability and prognosis of stroke patients. In patients with acute ischemic stroke, Hcy levels were significantly higher than the controls (p = 0.003). There was no significant difference between Lp(a) levels in patients with acute ischemic stroke and controls (p = 0.150). Since there was a significant difference in terms of Hcy levels between the groups it will be suitable to routinely monitor the Hcy levels of individuals who are known to have risk factors for stroke. Neither Lp(a) nor Hcy levels had any correlations with functional disability; therefore it can be concluded that the Lp(a) and Hcy levels are inexpressive in predicting the functional disability and prognosis for ischemic stroke patients.
Authors:
Elif Unal; Semra Mungan; Sule Bilen; Yesim Karadag; Nese Oztekin; Fatih Bakir; Fikri Ak
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-2-5
Journal Detail:
Title:  The International journal of neuroscience     Volume:  -     ISSN:  1563-5279     ISO Abbreviation:  Int. J. Neurosci.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-2-6     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0270707     Medline TA:  Int J Neurosci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
1Ankara Numune Education and Research Hospital , Neurology, Ankara , Turkey.
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